Equine Coat Color Genetics

 

Lesson Nine

 

The Appaloosa

 

 

Like the terms “Paint” and “Pinto”, “Appaloosa” refers to both a breed and a color.  Like those terms, when capitalized it means a horse of that breed, and when not, it means the color.  Just as the terms “paint” and (more commonly) “pinto” are used to refer to horses of any breed with white body spotting, so has the term “appaloosa” been used to refer to that pattern, regardless of breed.  In Europe it is usually called “spotted”.  Although the Appaloosa breed gave its name to the color, it is far from the only breed in which the pattern occurs.  Spotted horses have been found in Chinese art dating back as far as 500 BC.  By the 1300s they were common in Spain and by the early 1800s their presence was well established on the North American continent as the horse of the Nez Perce Indians.  Tribal legend of the Nez Perce indicate that the first '"spotted horses" arrived aboard a Russian ship in the early 1700s.   The horses were traded to Indians in the northwest who in turn traded them to the Nez Perce.  Other stories credit Cortez and the early Spanish explorers with the infusion of the Appaloosa into the Americas in the early 15th century.  

The breed registry for the Appaloosa horse is the Appaloosa Horse Club (ApHC)  http://www.appaloosa.com/

This registry has standardized names for the various types of appaloosa patterning and characteristics, as the Paint and Pinto registries did with pattern names like tobiano, overo, and so on.  As with the pinto spotting patterns, the size of the white areas is independent of the actual pattern gene, so can vary from large to small. 

A group of researchers and Appaloosa breeders formed a project to identify and map the Appaloosa genetics.  You can read more on The Appaloosa Project at:  https://www.appaloosaproject.co/

 

 

Appaloosa Characteristics

 

Just as the Dun gene causes a set of specific “dun-factor” markings, and the Champagne gene causes a unique skin color, the appaloosa color comes with some special characteristics of its own, in addition to any colorful pattern the horse may carry (or not).  These characteristics are varnish roan, mottled skin, white sclera, and striped hooves.  Another characteristic which is quite common but not universal is a short, sparse mane and tail (in the Appaloosa breed this is often called a “rat tail” and is considered a sign of “old blood” or “foundation” type); this trait is one that most breeders have been trying to eliminate, with some success, so it apparently is not caused by the actual appaloosa color genes.

 

Mottled Skin

   

This characteristic is unique to the appaloosa color, and is visible wherever there is bare skin -  on the face, udder or sheath, and under the tail.  It can vary from horse to horse, and can also increase over time, but there should be at least some mottling present.  Not to be confused with the speckled champagne skin, which is pinkish with tiny dark spots that look like they were dabbed on with a brown or black felt-tip marker, the appaloosa mottling looks like pink spots on a dark base. 

 

 

White Sclera

The sclera is the white part of the eye which encircles the iris (the colored portion). The white sclera of the human eye is visible all the time, but horses typically do not have much white sclera visible unless they are looking forward or back.  The appaloosa's is more readily visible at all times.  While the visible white sclera is considered an appaloosa trait, by itself it is not sufficient to prove a horse is appaloosa, because it can occur randomly on other colors and breeds, especially if there is a large amount of white on the face. 

 

Striped Hooves

Bold and clearly defined vertical stripes on the hooves of the dark legs, either dark with tan stripes, or tan with dark stripes, is an appaloosa trait.  If the horse happens to have white markings on its legs (unrelated to its appaloosa color), those hooves won’t be striped.  Striped hooves alone are not proof of appaloosa color, because other things can cause them.  Some Cream dilutes have vertical stripes on their hooves, but this is much more subtle.  Silver dapples can have very bold, distinct stripes, especially when young.  When horses with white leg markings have ermine spots in them, that can create a stripe below each spot.  For comparison, here are some examples of non-appaloosa hoof striping. 

 

                                                                                          

                                                                                                      palomino striped hoof                               silver dapple striped hoof                    ermine spots with stripes

 

 

 

               Varnish roan or “appy roan”

 

Appaloosas have a specific type of roaning which is different from the true roan and other types of roan that we discussed earlier.  This roaning is typically called Varnish Roan.  Appaloosa roaning is somewhat like grey in that it is progressive over time (although the horse won’t go completely white as a grey would).  They start out dark, like a grey, and the roaning increases from year to year.  Like grey, it may be obvious at the first shedding, or they may stay dark for several years, but eventually it will occur.  Although the appearance can be mistaken for other types of roan, or even grey, there are differences.  The lightest area tends to be over the hips (which may or may not be spotted), and the roaning is not as uniform as other types of roan.  There are darker areas where the bones are closer to the skin, such as the point of hip and elbow, stifle, lower legs, the frontal bones of the face and above the eye.  The ears are also usually dark.  These areas may stay dark all the horse’s life. 

 

                                                                                        

                                                                                                                   Varnish roan

 

 

 

 

Appaloosa Patterns

 

In addition to the above general appaloosa characteristics, appaloosas usually have some sort of pattern.  Some don’t, and are “only” varnish roan, but the patterning is highly desirable and breeders strive to produce them. 

 

Just as the Paint and Pinto registries standardized pattern terms such as Tobiano and Overo, Appaloosas have their own pattern terms as well.  (In other breeds where these patterns occur, they may or may not use the same terminology, but for the most part they have been pretty universally adopted.)  White patterning that covers all or almost all of the body is called Leopard, while white patterning that covers the hindquarters is called Blanket.  The white areas can contain spots, or not (more on that later).  A leopard without spots is called a “few-spot” and a blanket without spots is called a “snowcap”. 

 

Leopard is used when the horse is 60% or more white.  It’s not uncommon for them to retain a good deal of dark color on the head and legs.  If the white patterning extends up onto the neck and shoulder, but doesn’t cover them entirely, this is commonly called a “near-leopard” or “suppressed leopard”. 

 

                                                                                                              

                                                                                                                         Leopard                                                                    Near-leopard

 

 

                                                                                                           

                                                                                                                  “Few-spot” leopard                                                                    Few-spot

 

 

Blanket is used for a white marking that does not go farther forward than the withers.  They can be just a small area on the top of the hips, or extend all the way down under the belly.  The Appaloosa registry has five classifications of blankets depending on how much of the body they cover. 

                                                                                                            

                                                                                                               Small blanket                                                                              Larger blanket

 

 

 

                                                                                                              

                                                                                                                        Snowcap                                                                                  Snowcap

 

Another pattern is called Snowflake.  This is not actually white patterning, and it’s not known what exactly causes it; most likely it’s a stage that some varnish roans go through, but that is not known for certain yet.  This is when there are many white spots on a dark background. 

 

                                                                                                                      

                                                                                                                                 Snowflake                                                                           Snowflake

 

 

How it works

The Appaloosa coloring is a bit more complex than any others so far.  The reason for this is because it’s not just one gene.  Think back to when we looked at the base colors, and remember how it takes a combination of two separate genes to get a bay – at least one “E” so that it can make black pigment, and then at least one “A” so the black is restricted to the points, instead of covering the whole body.  Recall how a red horse might have any of the different genes at the Agouti locus, but because there’s no black pigment for it to act on, there’s no visible effect.  The appaloosa colors are similar to that. 

The first gene is called “LP” for Leopard Complex.  It was named long ago, before much was known about genetics, and is actually a slight misnomer now – this is the gene that gives the appaloosa characteristics listed above – the mottled skin, visible sclera, striped hooves, and varnish roan.  It does not actually cause the pattern labeled Leopard.  LP is the basic appaloosa gene, without which a horse would not be any of the appaloosa colors, but additional genes are needed to get the white patterning.  Without those pattern genes, the horse will be “just” a varnish roan with appaloosa characteristics.  The LP gene is another incomplete dominant.  This should be a familiar term by now.  When heterozygous, any white patterning on the horse will contain dark (base color) spots that do not roan out over time as the varnish roan progresses (these would be the leopards and blankets).  When homozygous, the white areas will have no spots or only a few little ones (these would be the fewspots and snowcaps).  Some experts also state that the heterozygous ones have dark hooves with light stripes, while the homozygous ones have light hooves with dark stripes (on legs without any white markings, of course). 

When homozygous, the LP gene also causes night blindness (full name: Congenital Stationary Night Blindness).  Most horses see much better in the dark than humans, but horses with night blindness see very little in the dark.  Surprisingly, they seem to cope with this very well, as with the Splash pintos that are deaf.  It took a long time for us humans to realize that these horses were deaf, or night-blind, as the case may be.  This condition is in place from birth and does not change throughout their lives. 

It is commonly believed that appaloosas in general tend to be more prone to uveitis, another eye condition, but there is no solid evidence linking it to the appaloosa genes.  Most experts think it’s caused by some sort of virus, but it’s not known why appaloosas would be more susceptible. 

The LP gene is located on chromosome 1, and was isolated in 2013.  There is now a test for it. 

But in addition to LP, an entirely different, separate gene is needed to get the white patterning.  So far only one has been isolated, in 2015.  It’s located on chromosome 3, and was named PATN1.  It is a simple dominant.  PATN1 causes the leopard/fewspot pattern, defined as 60-100% white.  Like the various pinto-spotting genes, there are undoubtedly other factors that influence the amount of white.  Usually leopards are white all over the body, with some dark on the head and legs.  But some have mixed or even dark areas extending back from the head, even including the whole neck and chest sometimes.  These are commonly called “semi-leopard” or “suppressed leopard”.  In the past it could be hard to tell for sure whether a horse was a semi-leopard or an extended-blanket pattern, but now that there is a test for the PATN1 gene, this can be determined.  A horse that has one or two PATN1 genes, and one LP gene, will be a leopard appaloosa:  white covering all or most of the body, with dark (base color) spots scattered throughout.  The spots are often larger and more numerous over the hindquarters.  A horse that has one or two PATN1 genes, and two LP genes, will be a few-spot appaloosa:  white covering all or most of the body, with no (or a very few small) spots.  A horse that is homozygous for both, LP/LP + PATN1/PATN1 will, when bred to solid mates, produce 100% leopard patterned offspring. 

When the research into the pattern genes was underway, it was hoped that there would be a second gene (which would be named PATN2) that causes the blanket pattern.  Unfortunately, no such gene has been found.  The researchers now believe that the blanket patterns are probably caused by many pattern genes, each of which has a small effect, so that a horse with a very small blanket might have just one of these genes, while a horse with an extensive blanket would have several of these genes.  And such a horse could pass on none, or some, or all of them, so that its offspring would range from no blanket, through various sizes of blankets, to ones that looked the parent, with smaller numbers at each extreme.  This does appear to be the way they produce.  But these pattern genes have not been identified yet.  It may be that some of the white-spotting (“W”) genes in the KIT complex can affect appaloosa patterns as well. 

There is a nice article on the Appaloosa Project website which has illustrated Punnett Square examples demonstrating the odds of various results when breeding Appaloosas, here:  

https://www.appaloosaproject.co/articles/free-articles/12-inheritance-information-for-appaloosa-specific-congenital-stationary-night-blindness.html

 

The interesting thing about this “two-genes-needed” inheritance of the appaloosa color, is that horses can carry the various pattern genes without showing any outward sign of it, if they don’t have at least one LP gene.  We have seen similar situations before; for instance a red-based horse can carry a Silver gene without showing it, even though it’s dominant, because Silver only affects black pigment and the red horse has none.  And as previously mentioned, a red-based horse does not show which genes it carries at the Agouti locus, since they too only affect black pigment.  It is completely unknown what percentage of solid-colored horses in breeds that once came in appaloosa colors but no longer do, or which go back to “unknowns” fairly recently, could possibly be carrying PATN1 and whatever other patterning genes that cause the blanket pattern.  It explains how the rare “crop-out” appaloosa can appear in breeds that were thought not to have those colors, such as the Quarter Horse and Tennessee Walking Horse.  One parent carried the pattern gene, unseen for generations, and the other parent had the LP gene although misidentified as a regular roan, or thought to be grey, or even covered up by an actual grey or roan color.  The foal gets both, and - surprise – an appaloosa baby.

As mentioned at the beginning, the appaloosa coloring is very old.  It appears to have been popular at various times in history, and then fallen out of favor at other times.  While it would be easy enough for a breed to eliminate LP because it’s visible (especially if that breed didn’t have any roans or greys for it to be mistaken for), the PATN genes would not be as easy to remove from the gene pool, since they are invisble without LP.   It would be a fascinating project to test a large number of solid colored horses from breeds which once had the coloring, or ties to breeds that did, and see if any are carrying PATN1.